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KMID : 0882420070730020142
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Korean Journal of Medicine
2007 Volume.73 No. 2 p.142 ~ p.150
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Clinical features and prognostic factors in Korean patients hospitalized for coronary artery disease (Catholic Heart Care Network Study).
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Cho Jin-Man
Kim Chong-Jin
Shin Woo-Sung
Cho Eun-Ju
Park Chul-Soo
Kim Pum-Joon
Lee Jong-Min
Ihm Sang-Hyun
Rhim Hyou-young
Chang Ki-Yuk
Moon Gun-Woong
Kim Yong-Joo
Jung Hae-Ok
Kim Hee-Yeol
Park Ji-Won
Jin Seung-Won
Jeon Hui-Kyung
Oh Yong-Seog
You Ki-Dong
Jeon Doo-Soo
Baek Sang-Hong
Lee Gil-Whan
Youn Ho-Joong
Lee Man-Young
Chung Wook-Sung
Park Jun-Chul
Seung Ki-Bae
Rho Tai-Ho
Kim Chul-Min
Park In-Soo
Chae Jang-Seong
Kim Jae-Hyung
Choi Kyu-Bo
Hong Soon-Jo
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Abstract
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Background:Coronary artery disease (CAD) has recently become one of the major causes of mortality and morbidity in Korea. However, not much epidemiologic and demographic data has yet been reported. The purpose of this study was to investigate the clinical features as well as the prognostic factors of patients with CAD.
Methods:We prospectively enrolled 1,665 consecutive patients with CAD who had been admitted to the Catholic University Hospitals from December 1999 to April 2003.
Results: Acute myocardial infarction (AMI) was the most common cause of admission (n=715, 42.9%). Dyslipidemia, hypertension and smoking were the most common risk factors. More than 70% of the patients who underwent percutaneous coronary intervention (PCI) received stent implantation. A total of 965 (612 males) patients were followed at least for 6 months (the mean follow-up duration was 23.8+/-12.2 months). The incidence rates of major adverse cardiac events (MACE: cardiac death, acute myocardial infarction, target vessel revascularization) and cardiac death were 15.1% (n=146) and 2.2% (n=21), respectively. There was no difference in overall survival between the patients treated with medical therapy and those treated with PCI. By Cox regression analysis, the independent prognostic factors for MACE were PCI (95% CI: 1.75-4.85; p<0.01) and multivessel disease (95% CI: 1.03-2.04; p<0.05), and the independent prognostic factors for cardiac death were medical therapy (95% CI: 1.08-14.41; p<0.05) and old age (95% CI: 1.13-16.13; p<0.05).
Conclusions:There was no difference in overall survival between the patients treated with medical therapy and those treated with PCI. However, PCI was superior to medical therapy for preventing death of the patients with acute coronary syndrome.
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KEYWORD
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Coronary disease, Intervention, Prognosis
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